Diagnostic and prognostic value of neutrophil gelatinase associated lipocalin and cancer antigen 15-3 serum levels in benign and malignant breast disease

Purpose: Increased neutrophil gelatinase-associated lipocalin (NGAL) serum levels have been shown in studies for colorectal, gastric, esophageal, liver, thyroid and lung cancer.The aim of this study was to demonstrate the differences of NGAL and cancer antigen 15-3 (CA15-3) serum levels between the groups of patients diagnosed with either breast ca

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Predicting the Threat Status of Mosses Using Functional Traits

Mosses are an early lineage of the plant kingdom, with around 13,000 species.Although an important part of biodiversity, providing crucial ecosystem services, many species are threatened with extinction.However, only circa 300 species have so far had their extinction risk evaluated globally for the IUCN Red List.Functional traits are known to help

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The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation

Successfully completing the S phase of each cell cycle ensures genome integrity.Impediment of DNA replication can lead to DNA damage and genomic disorders.In this study, we show a novel function for NDE1, Portable Speakers whose mutations cause brain developmental disorders, in safeguarding the genome through S phase during early steps of neural pr

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